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Catahoula Owners, Breeders & Research Association Catahoula Owners, Breeders & Research Association
Wednesday, December 04th 2013

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Catahoula Articles

  • The gene for merle in the dog has been identified and sequenced: Leigh Anne Clark, Jacquelyn M. Wahl, Christine A. Rees, and Keith E. Murphy. Retrotransposon insertion in SILV is responsible for merle patterning of the domestic dog. Proceedings of the National Academy of Sciences, 9 January 2006, 10.1073/pnas.0506940103. Published on line. See also the commentary discussing the impact of this work by Richard Cordaux and Mark A. Batzer: Teaching an old dog new tricks: SINEs of canine genomic diversity. Proceedings of the National Academy of Sciences, 9 January 2006, 10.1073/pnas.0510714103.
  • DNA test for merle gene available: Based on the work (above) by Drs. Clark and Murphy, a test is now available to identify heterozygous (mM) or homozygous (MM) carriers of the dominant allele of the merle gene using cheek swabs. Deafness is especially associated with homozygous merles. See VetGen's web site for details.
  • Also, the canine genome has been sequenced: K. Lindblad-Koh et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature, 8 December 2005, doi:10.1038/nature04338. Copy available here.


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